oa Microplasma-Sprayed Titanium and Hydroxyapatite Coatings on Ti6Al4V Alloy: in vitro Biocompatibility and Corrosion Resistance  

This paper investigates the bioactivity and mechanical properties of coatings applied to Ti6Al4V, a common titanium alloy used in endoprosthetic implants. Coatings made from hydroxyapatite (HA) powder and commercially pure titanium (CP Ti) wires were applied using microplasma spraying. The study focuses on the responses of rat mesenchymal stem cells (MSCs), which are essential for bone healing, to these coatings. By adjusting the microplasma spraying process, coatings with varying porosity and surface roughness were achieved. Results show that HA coatings significantly enhance MSC proliferation by 13% compared to the titanium alloy base, while Ti coatings also exhibit an 11% increase. Porosity inversely affects CP Ti's elasticity. Coatings with lower porosity demonstrate better corrosion resistance. HA coatings promote osteogenic activity and angiogenesis, which is crucial for implant integration.