-
oa Modelling Reactions at the Active Sites of Chiral Ruthenium Catalysts Using Density Functional Theory
NEW APPROACH TO UNDERSTANDING OF CATALYTIC REACTIONS
- Source: Platinum Metals Review, Volume 51, Issue 2, Apr 2007, p. 54 - 62
-
- 01 Jan 2007
- Previous Article
- Table of Contents
- Next Article
Abstract
Selectivity is a key success factor in the chiral catalyst technologies market. Understanding the fundamental processes that occur when a reagent interacts with a homogeneous single site catalyst, both in its approach and at the active site, is therefore critical to the rational design of new catalysts. Ruthenium-based asymmetric hydrogenation catalysts have been considered as part of a collaborative research project. [(S)-XylBINAP-RuH2-(S,S)-DPEN], first developed by Noyori (1–3), is studied as the parent or prototype model of a series of efficient hydrogenation catalysts, among them the catalysts based on the P-Phos, PhanePhos and ParaPhos ligand families (4).
© Johnson Matthey