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oa The Mechanism of Action of Anti-tumour Platinum Compounds
- Source: Platinum Metals Review, Volume 21, Issue 1, Jan 1977, p. 2 - 15
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- 01 Jan 1977
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Abstract
A wide range of studies carried out by cell biologists and biochemists lead to the conclusion that platinum anti-tumour compounds exert their potency by stopping the replication of DNA, thereby preventing cell division. This is most likely achieved by the formation of a complex between the bases of the DNA and the platinum compounds. The exact nature of this binding is not yet understood.
© Johnson Matthey