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Volume 62, Issue 3
  • ISSN: 2056-5135
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Abstract

With a design guided by computational fluid dynamics (CFD), additively manufactured from base metals and coated with metal catalysts using cold spray technology or electroplating, catalytic static mixers are used to replace fixed bed columns in continuous flow reactors. We have shown their versatility in gas-liquid hydrogenations and homogeneous transfer hydrogenations and review here their preparation, stability and wider use in catalytic transformations using flow reactors. Additive manufacturing provides complex mixer structures that can be retrofitted to existing reactor geometry and reduces manufacturing costs by removing abrasive blasting steps in the mixer fabrication process. The rough surface profile of the mixers aids with high metallurgical bonding of the catalyst coating, as shown by the low catalyst leaching levels reported here.

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2018-01-01
2024-11-21
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References

  1. J. Wegner, S. Ceylan, A. Kirschning, Chem. Commun., 2011, 47, (16), 4583 LINK https://doi.org/10.1039/c0cc05060a [Google Scholar]
  2. F. Darvas, G. Dormán, G. Dormán, V. Hessel, ‘Fundamentals of Flow Chemistry’, in “Flow Chemistry: Fundementals”, eds. F. Darvas, 1, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 9–58 [Google Scholar]
  3. L. N. Protasova, M. Bulut, D. Ormerod, A. Buekenhoudt, J. Berton, C. V. Stevens, Org. Process Res. Dev., 2013, 17, (5), 760 LINK https://doi.org/10.1021/op4000169 [Google Scholar]
  4. M. Baumann, I. R. Baxendale, Beilstein J. Org. Chem., 2015, 11, 1194 LINK https://doi.org/10.3762/bjoc.11.134 [Google Scholar]
  5. R. Porta, M. Benaglia, A. Puglisi, Org. Process Res. Dev., 2016, 20, (1), 2 LINK https://doi.org/10.1021/acs.oprd.5b00325 [Google Scholar]
  6. B. Gutmann, D. Cantillo, C. O. Kappe, Angew. Chem. Int. Ed., 2015, 54, (23), 6688 LINK https://doi.org/10.1002/anie.201409318 [Google Scholar]
  7. M. Movsisyan, E. I. P. Delbeke, J. K. E. T. Berton, C. Battilocchio, S. V. Ley, C. V. Stevens, Chem. Soc. Rev., 2016, 45, (18), 4892 LINK https://doi.org/10.1039/C5CS00902B [Google Scholar]
  8. P. J. Cossar, L. Hizartzidis, M. I. Simone, A. McCluskey, C. P. Gordon, Org. Biomol. Chem., 2015, 13, (26), 7119 LINK https://doi.org/10.1039/C5OB01067E [Google Scholar]
  9. C. Brechtelsbauer, K. K. Hii, V. Hessel, G. Dormán, ‘Catalysis in Flow’, in “Flow Chemistry: Applications”, eds. F. Darvas, 2, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 3–30 [Google Scholar]
  10. C. de Bellefon, V. Hessel, G. Dormán, ‘Catalytic Engineering Aspects of Flow Chemistry’, in “Flow Chemistry: Applications”, eds. F. Darvas, 2, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 31–62 [Google Scholar]
  11. R. V. Jones, L. Godorhazy, N. Varga, D. Szalay, L. Urge, F. Darvas, J. Comb. Chem., 2006, 8, (1), 110 LINK https://doi.org/10.1021/cc050107o [Google Scholar]
  12. J. Singh, Chim. e Ind., 2011, 93, (8), 132 LINK https://www.soc.chim.it/sites/default/files/chimind/pdf/2011_8_132_ca.pdf [Google Scholar]
  13. J. Yue, Catal. Today, 2018, 308, 3 LINK https://doi.org/10.1016/j.cattod.2017.09.041 [Google Scholar]
  14. B. R. Vaddula, R. S. Varma, M. A. A. Gonzalez, Curr. Org. Chem., 2013, 17, (20), 2268 LINK https://doi.org/10.2174/13852728113179990041 [Google Scholar]
  15. T. Chinnusamy, S. S Yudha, M. Hager, P. Kreitmeier, O. Reiser, ChemSusChem, 2012, 5, (2), 247 LINK https://doi.org/10.1002/cssc.201100444 [Google Scholar]
  16. A. Avril, C. H. Hornung, A. Urban, D. Fraser, M. Horne, J.-P. Veder, J. Tsanaktsidis, T. Rodopoulos, C. Henry, D. Gunasegaram, React. Chem. Eng., 2017, 2, (2), 180 LINK https://doi.org/10.1039/C6RE00188B [Google Scholar]
  17. C. H. Hornung, X. Nguyen, A. Carafa, J. Gardiner, A. Urban, D. Fraser, M. D. Horne, D. R. Gunasegaram, J. Tsanaktsidis, Org. Process Res. Dev., 2017, 21, (9), 1311 LINK https://doi.org/10.1021/acs.oprd.7b00180 [Google Scholar]
  18. X. Nguyen, A. Carafa, C. H. Hornung, Chem. Eng. Process. Process Intensif., 2018, 124, 215 LINK https://doi.org/10.1016/j.cep.2017.12.007 [Google Scholar]
  19. “CSIRO Additive Manufacturing of Metals”, CSIRO, online video clip, CSIRO, YouTubeGB, 13th January, 2013 LINK https://www.youtube.com/watch?v=OSIImvwfNns
  20. ‘CSIRO Produces 3D Heel in World First Surgery’, CSIRO, Canberra, Australia, 22nd October, 2014 LINK https://csiropedia.csiro.au/csiro-produces-3d-heel-in-world-first-surgery/ [Google Scholar]
  21. A. Knight, ‘Cancer Patient Receives 3D Printed Ribs in World-First Surgery’, CSIRO, Canberra, Australia, 11th September, 2015 LINK https://blog.csiro.au/cancer-patient-receives-3d-printed-ribs-in-world-first-surgery/ [Google Scholar]
  22. ‘Safety Standard for Hydrogen and Hydrogen Systems: Guidelines for Hydrogen System Design, Materials Selection, Operations, Storage and Transportation’, NSS-1740.16-Rev, Office of Safety and Mission Assurance, NASA, Washington DC, USA, 1st January, 1997 LINK http://hdl.handle.net/2060/19970033338 [Google Scholar]
  23. A. Barnoush, H. Vehoff, Acta Mater., 2010, 58, (16), 5274 LINK https://doi.org/10.1016/j.actamat.2010.05.057 [Google Scholar]
  24. D. S. Shih, I. M. Robertson, H. K. Birnbaum, Acta Metall., 1988, 36, (1), 111 LINK https://doi.org/10.1016/0001-6160(88)90032-6 [Google Scholar]
  25. J. Gardiner, C. H. Hornung, X. Nguyen, A. J. Urban, D. Fraser, D. Gunasegaram, M. D. Horne, J. Tsanaktsidis, ‘Continuous Flow Hydrogenations Using Catalytic Static Mixers: Application to a Key Pharmaceutical Intermediate of Linezolid’, Poster 646, 18th Tetrahedron Symposium Asian Edition, Melbourne, Australia, 24th–26th July, 2017 [Google Scholar]
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Additive Layer Manufacturing of Catalytic Static Mixers for Continuous Flow Reactors
Johnson Matthey Technology Review 62, 350 (2018); https://doi.org/10.1595/205651318X696846
/content/journals/10.1595/205651318X696846
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  • Article Type: Research Article

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