Skip to content
1887
  1. Home
  2. A-Z Publications
  3. Johnson Matthey Technology Review
  4. Volume 62, Issue 3
  5. Article
Volume 62, Issue 3
  • ISSN: 2056-5135
file format pdf download PDF

Abstract

With a design guided by computational fluid dynamics (CFD), additively manufactured from base metals and coated with metal catalysts using cold spray technology or electroplating, catalytic static mixers are used to replace fixed bed columns in continuous flow reactors. We have shown their versatility in gas-liquid hydrogenations and homogeneous transfer hydrogenations and review here their preparation, stability and wider use in catalytic transformations using flow reactors. Additive manufacturing provides complex mixer structures that can be retrofitted to existing reactor geometry and reduces manufacturing costs by removing abrasive blasting steps in the mixer fabrication process. The rough surface profile of the mixers aids with high metallurgical bonding of the catalyst coating, as shown by the low catalyst leaching levels reported here.

© Johnson Matthey
Loading

Article metrics loading...

/content/journals/10.1595/205651318X696846
2018-01-01
2024-04-19
Loading full text...

Full text loading...

/deliver/fulltext/jmtr/62/3/Saubern_16a_Imp.html?itemId=/content/journals/10.1595/205651318X696846&mimeType=html&fmt=ahah

References

  1. Wegner J., Ceylan S., and Kirschning A. Chem. Commun., 2011, 47, (16), 4583 LINK https://doi.org/10.1039/c0cc05060a [Google Scholar]
  2. Darvas F., Dormán G., Dormán G., and Hessel V. ‘Fundamentals of Flow Chemistry’, in “Flow Chemistry: Fundementals”, eds. Darvas F., 1, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 9–58 [Google Scholar]
  3. Protasova L. N., Bulut M., Ormerod D., Buekenhoudt A., Berton J., and Stevens C. V. Org. Process Res. Dev., 2013, 17, (5), 760 LINK https://doi.org/10.1021/op4000169 [Google Scholar]
  4. Baumann M., and Baxendale I. R. Beilstein J. Org. Chem., 2015, 11, 1194 LINK https://doi.org/10.3762/bjoc.11.134 [Google Scholar]
  5. Porta R., Benaglia M., and Puglisi A. Org. Process Res. Dev., 2016, 20, (1), 2 LINK https://doi.org/10.1021/acs.oprd.5b00325 [Google Scholar]
  6. Gutmann B., Cantillo D., and Kappe C. O. Angew. Chem. Int. Ed., 2015, 54, (23), 6688 LINK https://doi.org/10.1002/anie.201409318 [Google Scholar]
  7. Movsisyan M., Delbeke E. I. P., Berton J. K. E. T., Battilocchio C., Ley S. V., and Stevens C. V. Chem. Soc. Rev., 2016, 45, (18), 4892 LINK https://doi.org/10.1039/C5CS00902B [Google Scholar]
  8. Cossar P. J., Hizartzidis L., Simone M. I., McCluskey A., and Gordon C. P. Org. Biomol. Chem., 2015, 13, (26), 7119 LINK https://doi.org/10.1039/C5OB01067E [Google Scholar]
  9. Brechtelsbauer C., Hii K. K., Hessel V., and Dormán G. ‘Catalysis in Flow’, in “Flow Chemistry: Applications”, eds. Darvas F., 2, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 3–30 [Google Scholar]
  10. de Bellefon C., Hessel V., and Dormán G. ‘Catalytic Engineering Aspects of Flow Chemistry’, in “Flow Chemistry: Applications”, eds. Darvas F., 2, Walter De Gruyter GmbH, Berlin, Germany, 2014, pp. 31–62 [Google Scholar]
  11. Jones R. V., Godorhazy L., Varga N., Szalay D., Urge L., and Darvas F. J. Comb. Chem., 2006, 8, (1), 110 LINK https://doi.org/10.1021/cc050107o [Google Scholar]
  12. Singh J. Chim. e Ind., 2011, 93, (8), 132 LINK https://www.soc.chim.it/sites/default/files/chimind/pdf/2011_8_132_ca.pdf [Google Scholar]
  13. Yue J. Catal. Today, 2018, 308, 3 LINK https://doi.org/10.1016/j.cattod.2017.09.041 [Google Scholar]
  14. Vaddula B. R., Varma R. S., and Gonzalez M. A. A. Curr. Org. Chem., 2013, 17, (20), 2268 LINK https://doi.org/10.2174/13852728113179990041 [Google Scholar]
  15. Chinnusamy T., Yudha S. S, Hager M., Kreitmeier P., and Reiser O. ChemSusChem, 2012, 5, (2), 247 LINK https://doi.org/10.1002/cssc.201100444 [Google Scholar]
  16. Avril A., Hornung C. H., Urban A., Fraser D., Horne M., Veder J.-P., Tsanaktsidis J., Rodopoulos T., Henry C., and Gunasegaram D. React. Chem. Eng., 2017, 2, (2), 180 LINK https://doi.org/10.1039/C6RE00188B [Google Scholar]
  17. Hornung C. H., Nguyen X., Carafa A., Gardiner J., Urban A., Fraser D., Horne M. D., Gunasegaram D. R., and Tsanaktsidis J. Org. Process Res. Dev., 2017, 21, (9), 1311 LINK https://doi.org/10.1021/acs.oprd.7b00180 [Google Scholar]
  18. Nguyen X., Carafa A., and Hornung C. H. Chem. Eng. Process. Process Intensif., 2018, 124, 215 LINK https://doi.org/10.1016/j.cep.2017.12.007 [Google Scholar]
  19. “CSIRO Additive Manufacturing of Metals”, CSIRO, online video clip, CSIRO, YouTubeGB, 13th January, 2013 LINK https://www.youtube.com/watch?v=OSIImvwfNns
  20. ‘CSIRO Produces 3D Heel in World First Surgery’, CSIRO, Canberra, Australia, 22nd October, 2014 LINK https://csiropedia.csiro.au/csiro-produces-3d-heel-in-world-first-surgery/ [Google Scholar]
  21. Knight A. ‘Cancer Patient Receives 3D Printed Ribs in World-First Surgery’, CSIRO, Canberra, Australia, 11th September, 2015 LINK https://blog.csiro.au/cancer-patient-receives-3d-printed-ribs-in-world-first-surgery/ [Google Scholar]
  22. ‘Safety Standard for Hydrogen and Hydrogen Systems: Guidelines for Hydrogen System Design, Materials Selection, Operations, Storage and Transportation’, NSS-1740.16-Rev, Office of Safety and Mission Assurance, NASA, Washington DC, USA, 1st January, 1997 LINK http://hdl.handle.net/2060/19970033338 [Google Scholar]
  23. Barnoush A., and Vehoff H. Acta Mater., 2010, 58, (16), 5274 LINK https://doi.org/10.1016/j.actamat.2010.05.057 [Google Scholar]
  24. Shih D. S., Robertson I. M., and Birnbaum H. K. Acta Metall., 1988, 36, (1), 111 LINK https://doi.org/10.1016/0001-6160(88)90032-6 [Google Scholar]
  25. Gardiner J., Hornung C. H., Nguyen X., Urban A. J., Fraser D., Gunasegaram D., Horne M. D., and Tsanaktsidis J. ‘Continuous Flow Hydrogenations Using Catalytic Static Mixers: Application to a Key Pharmaceutical Intermediate of Linezolid’, Poster 646, 18th Tetrahedron Symposium Asian Edition, Melbourne, Australia, 24th–26th July, 2017 [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.1595/205651318X696846
Loading
Additive Layer Manufacturing of Catalytic Static Mixers for Continuous Flow Reactors
Johnson Matthey Technology Review 62, 350 (2018); https://doi.org/10.1595/205651318X696846
/content/journals/10.1595/205651318X696846
/content/journals/10.1595/205651318X696846
Loading

Data & Media loading...

  • Article Type: Research Article

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error