Skip to content
1887
Volume 63, Issue 3
  • ISSN: 2056-5135

Abstract

The formulation and delivery of the biologically active ingredients (AIs) (for example, agrochemicals and active pharmaceutical ingredients (APIs)) is an inherently interdisciplinary area of research and development. In this short review we discuss the evolution of AI and API delivery systems towards smart stimuli-responsive formulations with precisely controlled delivery for specific applications. We also highlight a few examples of such systems using AIs from Johnson Matthey’s controlled substance and API portfolio.

Loading

Article metrics loading...

/content/journals/10.1595/205651319X15585277727868
2019-01-01
2024-02-27
Loading full text...

Full text loading...

/deliver/fulltext/jmtr/63/3/Hardy_16a_Imp.html?itemId=/content/journals/10.1595/205651319X15585277727868&mimeType=html&fmt=ahah

References

  1. Atanasov A. G., Waltenberger B., Pferschy-Wenzig E.-M., Linder T., Wawrosch C., Uhrin P., Temml V., Wang L., Schwaiger S., Heiss E. H., Rollinger J. M., Schuster D., Breuss J. M., Bochkov V., Mihovilovic M. D., Kopp B., Bauer R., Dirsch V. M., and Stuppner H. Biotechnol. Adv., 2015, 33, (8), 1582 LINK https://doi.org/10.1016/j.biotechadv.2015.08.001 [Google Scholar]
  2. Anselmo A. C., and Mitragotri S. J. Control. Release, 2014, 190, 15 LINK https://doi.org/10.1016/j.jconrel.2014.03.053 [Google Scholar]
  3. Dixon S. J., and Stockwell B. R. Nature Chem. Biol., 2010, 6, (5), 318 LINK https://doi.org/10.1038/nchembio.353 [Google Scholar]
  4. Sneader W. “Drug Discovery: A History”, John Wiley and Sons Ltd, Chichester, UK, 2005, 468 pp LINK https://doi.org/10.1002/0470015535 [Google Scholar]
  5. Kirsch D. R., ‘Therapeutic Drug Development and Human Clinical Trials’, in “Biotechnology Entrepreneurship: Starting, Managing, and Leading Biotech Companies”, ed. and Shimasaki C. Elsevier Inc, Waltham, USA, 2014, pp. 315330 LINK https://doi.org/10.1016/b978-0-12-404730-3.00023-3 [Google Scholar]
  6. Turner M. A., Catapano M., Hirschfeld S., and Giaquinto C. Adv. Drug Deliv. Rev., 2014, 73, 2 LINK https://doi.org/10.1016/j.addr.2014.02.003 [Google Scholar]
  7. Tiwari G., Tiwari R., Sriwastawa B., Bhati L., Pandey S., Pandey P., and Bannerjee S. Int. J. Pharm. Investig., 2012, 2, (1), 2 LINK https://doi.org/10.4103/2230-973x.96920 [Google Scholar]
  8. Sinha P. M., Valco G., Sharma S., Liu X., and Ferrari M. Nanotechnol., 2004, 15, (10), S585 LINK https://doi.org/10.1088/0957-4484/15/10/015 [Google Scholar]
  9. Lutgens L., van der Zee J., Pijls-Johannesma M., De Haas-Kock D. F. M., Buijsen J., van Mastrigt G. A. P. G., Lammering G., De Ruysscher D. K. M., and Lambin P. Cochrane Database Syst. Rev., 2010, (3), CD 006377 LINK https://doi.org/10.1002/14651858.cd006377.pub3 [Google Scholar]
  10. Lieder A., Khan M. K., and Lippert B. M. Cochrane Database Syst. Rev., 2014, (6), CD009810 LINK https://doi.org/10.1002/14651858.cd009810.pub2 [Google Scholar]
  11. Tharyan P., and Adams C. E. Cochrane Database Syst. Rev., 2005, (2), CD000076 LINK https://doi.org/10.1002/14651858.CD000076.pub2 [Google Scholar]
  12. Woolcock J. G., Grivell R. M., and Dodd J. M. Cochrane Database Syst. Rev., 2014, (11), CD011371 LINK https://doi.org/10.1002/14651858.cd011371 [Google Scholar]
  13. Shada A. L., Dengel L. T., Petroni G. R., Smolkin M. E., Acton S., and Slingluff C. L. J. Surg. Res., 2013, 182, (1), e9 LINK https://doi.org/10.1016/j.jss.2012.09.022 [Google Scholar]
  14. Khandare J., and Minko T. Prog. Polym. Sci., 2006, 31, (4), 359 LINK https://doi.org/10.1016/j.progpolymsci.2005.09.004 [Google Scholar]
  15. Vashist A., Vashist A., Gupta Y. K., and Ahmad S. J. Mater. Chem. B, 2014, 2, (2), 147 LINK https://doi.org/10.1039/c3tb21016b [Google Scholar]
  16. Maity A. R., and Stepensky D. Mol. Pharmaceutics, 2016, 13, (1), 1 LINK https://doi.org/10.1021/acs.molpharmaceut.5b00697 [Google Scholar]
  17. Dhand C., Prabhakaran M. P., Beuerman R. W., Lakshminarayanan R., Dwivedi N., and Ramakrishna S. RSC Adv., 2014, 4, (62), 32673 LINK https://doi.org/10.1039/c4ra02861a [Google Scholar]
  18. Toon R. C., Preedy E. C., and Prokopovich P. Eurasian Chem. Tech. J., 2012, 14, (4), 271 LINK https://doi.org/10.18321/ectj124 [Google Scholar]
  19. Walter M. W. Nat. Prod. Rep., 2002, 19, (3), 278 LINK https://doi.org/10.1039/b100919m [Google Scholar]
  20. Verma R. K., Mishra B., and Garg S. Drug Dev. Ind. Pharm., 2000, 26, (7), 695 LINK https://doi.org/10.1081/ddc-100101287 [Google Scholar]
  21. Park K. J. Control. Release, 2014, 190, 3 LINK https://doi.org/10.1016/j.jconrel.2014.03.054 [Google Scholar]
  22. Park K. Mol. Pharmaceutics, 2016, 13, (7), 2143 LINK https://doi.org/10.1021/acs.molpharmaceut.6b00015 [Google Scholar]
  23. Park K. J. Control. Release, 2016, 240, 2 LINK https://doi.org/10.1016/j.jconrel.2015.10.048 [Google Scholar]
  24. van Kammen D. P., Docherty J. P., Marder S. R., Rayner J. N., and Bunney W. E. Jr Arch. Gen. Psychiatry, 1982, 39, (3), 275 LINK https://doi.org/10.1001/archpsyc.1982.04290030017003 [Google Scholar]
  25. Yun Y. H., Lee B. K., and Park K. J. Control. Release, 2015, 219, 2 LINK https://doi.org/10.1016/j.jconrel.2015.10.005 [Google Scholar]
  26. ‘Highlights of Prescribing Information – SEROQUEL® (Quetiapine Fumarate) Tablets, for Oral Use’, Reference ID 4060088, AstraZeneca, Wilmington, USA, February, 2017: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020639s065lbl.pdf (Accessed on 31st May 2019) [Google Scholar]
  27. Figueroa C., Brecher M., Hamer-Maansson J. E., and Winter H. Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 2009, 33, (2), 199 LINK https://doi.org/10.1016/j.pnpbp.2008.09.026 [Google Scholar]
  28. Good W. R., and Piraino A. J. J. Control. Release, 1990, 11, (1–3), 315 LINK https://doi.org/10.1016/0168-3659(90)90144-i [Google Scholar]
  29. Zhong H., Chan G., Hu Y., Hu H., and Ouyang D. Pharmaceutics, 2018, 10, (4), 263 LINK https://doi.org/10.3390/pharmaceutics10040263 [Google Scholar]
  30. and Langer R. “Biodegradable Polymers as Drug Delivery Systems”, eds. Chasin M., Drugs and the Pharmaceutical Sciences, Vol. 45, Marcel Dekker Inc, New York, USA, 1990, 347 pp [Google Scholar]
  31. Shieh L., Tamada J., Tabata Y., Domb A., and Langer R. J. Control. Release, 1994, 29, (1–2), 73 LINK https://doi.org/10.1016/0168-3659(94)90123-6 [Google Scholar]
  32. Kost J., and Langer R. Adv. Drug Deliv. Rev., 2012, 64, 327 LINK https://doi.org/10.1016/j.addr.2012.09.014 [Google Scholar]
  33. Uhrich K. E., Cannizzaro S. M., Langer R. S., and Shakesheff K. M. Chem. Rev., 1999, 99, (11), 3181 LINK https://doi.org/10.1021/cr940351u [Google Scholar]
  34. Hoffman A. S. J. Control. Release, 2008, 132, (3), 153 LINK https://doi.org/10.1016/j.jconrel.2008.08.012 [Google Scholar]
  35. Dosio F., Arpicco S., Stella B., and Fattal E. Adv. Drug Deliv. Rev., 2016, 97, 204 LINK https://doi.org/10.1016/j.addr.2015.11.011 [Google Scholar]
  36. Harris J. M., and Chess R. B. Nat. Rev. Drug Discov., 2003, 2, (3), 214 LINK https://doi.org/10.1038/nrd1033 [Google Scholar]
  37. Greenwald R. B. Puerto Rico Health Sci. J., 2002, 21, (2), 113 LINK http://prhsj.rcm.upr.edu/index.php/prhsj/article/download/885/604 [Google Scholar]
  38. Lee K.-S., Kim D. S., and Kim B. S. Biotechnol. Bioprocess Eng., 2007, 12, (2), 152 LINK https://doi.org/10.1007/bf03028642 [Google Scholar]
  39. Seong H., An T. K., Khang G., Choi S.-U., Lee C. O., and Lee H. B. Int. J. Pharm., 2003, 251, (1–2), 1 LINK https://doi.org/10.1016/s0378-5173(02)00543-4 [Google Scholar]
  40. Barnard C. Johnson Matthey Technol. Rev., 2017, 61, (1), 52 LINK https://www.technology.matthey.com/article/61/1/52-59/ [Google Scholar]
  41. Dhar S., Gu F. X., Langer R., Farokhzad O. C., and Lippard S. J. Proc. Natl. Acad. Sci., 2008, 105, (45), 17356 LINK https://doi.org/10.1073/pnas.0809154105 [Google Scholar]
  42. Srivastava A., Yadav T., Sharma S., Nayak A., Kumari A. A., and Mishra N. J. Biosci. Med., 2016, 04, (01), 69 LINK https://doi.org/10.4236/jbm.2016.41009 [Google Scholar]
  43. Zhao Z., Ding C., Wang Y., Tan H., and Li J. Biomater. Sci., 2019, 7, (4), 1643 LINK https://doi.org/10.1039/c8bm01640b [Google Scholar]
  44. Ensign L. M., Cone R., and Hanes J. Adv. Drug Deliv. Rev., 2012, 64, (6), 557 LINK https://doi.org/10.1016/j.addr.2011.12.009 [Google Scholar]
  45. Liu Z., Wang S., Hu M., Chen Y., Zhang G. G. Z., Liu L., and Porter W. R. ‘Oral Absorption Basics: Pathways, Physico-chemical and Biological Factors Affecting Absorption’, in “Developing Solid Oral Dosage Forms – Pharmaceutical Theory and Practice”, eds. Qiu Y., Elsevier Inc, Burlington, USA, 2009, pp. 265288 LINK https://doi.org/10.1016/b978-0-444-53242-8.00011-4 [Google Scholar]
  46. Carino G. P., Jacob J. S., and Mathiowitz E. J. Control. Release, 2000, 65, (1–2), 261 LINK https://doi.org/10.1016/s0168-3659(99)00247-3 [Google Scholar]
  47. Henkin R. I. Nutrition, 2010, 26, (1), 33 LINK https://doi.org/10.1016/j.nut.2009.08.001 [Google Scholar]
  48. Mutalik Venkatesh S., and Udupa N. Indian Drugs, 2002, 39, (6), 305 [Google Scholar]
  49. Paudel K. S., Milewski M., Swadley C. L., Brogden N. K., Ghosh P., and Stinchcomb A. L. Ther. Deliv., 2010, 1, (1), 109 LINK https://doi.org/10.4155/tde.10.16 [Google Scholar]
  50. Parrott A. C. Psychopharmacol., 1986, 89, (3), 347 LINK https://doi.org/10.1007/bf00174373 [Google Scholar]
  51. Moon J. M., and Chun B. J. J. Emerg. Med., 2011, 40, (1), 37 LINK https://doi.org/10.1016/j.jemermed.2007.10.075 [Google Scholar]
  52. Good W. R., Powers M. S., Campbell P., and Schenkel L. J. Control. Release, 1985, 2, 89 LINK https://doi.org/10.1016/0168-3659(85)90035-5 [Google Scholar]
  53. Godin B., and Touitou E. Adv. Drug Deliv. Rev., 2007, 59, (11), 1152 LINK https://doi.org/10.1016/j.addr.2007.07.004 [Google Scholar]
  54. Ko P.-T., Lee I.-C., Chen M.-C., and Tsai S.-W. J. Taiwan Inst. Chem. Eng., 2015, 51, 1 LINK https://doi.org/10.1016/j.jtice.2015.01.003 [Google Scholar]
  55. Kim Y.-C., Park J.-H., and Prausnitz M. R. Adv. Drug Deliv. Rev., 2012, 64, (14), 1547 LINK https://doi.org/10.1016/j.addr.2012.04.005 [Google Scholar]
  56. Sullivan S. P., Koutsonanos D. G., del Pilar Martin M., Lee J. W., Zarnitsyn V., Choi S.-O., Murthy N., Compans R. W., Skountzou I., and Prausnitz M. R. Nature Med., 2010, 16, (8), 915 LINK https://doi.org/10.1038/nm.2182 [Google Scholar]
  57. Khor S.-P., and Hsu A. Curr. Clin. Pharmacol., 2007, 2, (3), 234 LINK https://doi.org/10.2174/157488407781668802 [Google Scholar]
  58. Goonoo N., Bhaw-Luximon A., Ujoodha R., Jhugroo A., Hulse G. K., and Jhurry D. J. Control. Release, 2014, 183, 154 LINK https://doi.org/10.1016/j.jconrel.2014.03.046 [Google Scholar]
  59. Armaly M. F., and Rao K. R. Investig. Ophthalmol. Vis. Sci., 1973, 12, (7), 491 LINK https://iovs.arvojournals.org/article.aspx?articleid=2158352 [Google Scholar]
  60. Sampath Kumar K. P., Bhowmik D., Harish G., Duraivel S., and Pragathi kumar B. Pharma Innov., 2013, 1, (12), 1 LINK http://www.thepharmajournal.com/vol1Issue12/Issue_feb_2013/1.1.pdf [Google Scholar]
  61. Brem H. Biomater., 1990, 11, (9), 699 LINK https://doi.org/10.1016/0142-9612(90)90030-t [Google Scholar]
  62. Regnier-Delplace C., Thillaye du Boullay O., Siepmann F., Martin-Vaca B., Degrave N., Demonchaux P., Jentzer O., Bourissou D., and Siepmann J. Int. J. Pharm., 2013, 443, (1–2), 68 LINK https://doi.org/10.1016/j.ijpharm.2013.01.008 [Google Scholar]
  63. Yang G., Liu J., Wu Y., Feng L., and Liu Z. Coord. Chem. Rev., 2016, 320–321, 100 LINK https://doi.org/10.1016/j.ccr.2016.04.004 [Google Scholar]
  64. Tong R., Hemmati H. D., Langer R., and Kohane D. S. J. Am. Chem. Soc., 2012, 134, (21), 8848 LINK https://doi.org/10.1021/ja211888a [Google Scholar]
  65. Alvarez-Lorenzo C., Bromberg L., and Concheiro A. Photochem. Photobiol., 2009, 85, (4), 848 LINK https://doi.org/10.1111/j.1751-1097.2008.00530.x [Google Scholar]
  66. Yang P., Gai S., and Lin J. Chem. Soc. Rev., 2012, 41, (9), 3679 LINK https://doi.org/10.1039/c2cs15308d [Google Scholar]
  67. Mura S., Nicolas J., and Couvreur P. Nature Mater., 2013, 12, (11), 991 LINK https://doi.org/10.1038/nmat3776 [Google Scholar]
  68. Deckers R., and Moonen C. T. W. J. Control. Release, 2010, 148, (1), 25 LINK https://doi.org/10.1016/j.jconrel.2010.07.117 [Google Scholar]
  69. Schmidt D. J., Moskowitz J. S., and Hammond P. T. Chem. Mater., 2010, 22, (23), 6416 LINK https://doi.org/10.1021/cm102578j [Google Scholar]
  70. Lambin P., Zindler J., Vanneste B. G. L., Van De Voorde L., Eekers D., Compter I., Panth K. M., Peerlings J., Larue R. T. H. M., Deist T. M., Jochems A., Lustberg T., van Soest J., de Jong E. E. C., Even A. J. G., Reymen B., Rekers N., van Gisbergen M., Roelofs E., Carvalho S., Leijenaar R. T. H., Zegers C. M. L., Jacobs M., van Timmeren J., Brouwers P., Lal J. A., Dubois L., Yaromina A., Van Limbergen E. J., Berbee M., van Elmpt W., Oberije C., Ramaekers B., Dekker A., Boersma L. J., Hoebers F., Smits K. M., Berlanga A. J., and Walsh S. Adv. Drug Deliv. Rev., 2017, 109, 131 LINK https://doi.org/10.1016/j.addr.2016.01.006 [Google Scholar]
  71. Alvarez-Lorenzo C., and Concheiro A. Chem. Commun., 2014, 50, (58), 7743 LINK https://doi.org/10.1039/c4cc01429d [Google Scholar]
  72. Erkeçoğlu S., Sezer A. D., Bucak S., ‘Smart Delivery Systems with Shape Memory and Self-Folding Polymers’, in “Smart Drug Delivery Systems”, ed. and Sezer A. D. InTech, London, UK, 2016, 29 pp LINK https://doi.org/10.5772/62199 [Google Scholar]
  73. Peterson G. I., Dobrynin A. V, and Becker M. L. Adv. Healthcare Mater., 2017, 6, (21), 1700694 LINK https://doi.org/10.1002/adhm.201700694 [Google Scholar]
  74. Wischke C., Neffe A. T., Lendlein A., ‘Controlled Drug Release from Biodegradable Shape-Memory Polymers’, in “Shape-Memory Polymers”, ed. and Lendlein A. Advances in Polymer Science, Vol. 226, Springer-Verlag Berlin Heidelberg, Dordrecht, The Netherlands, 2010, pp. 177205 LINK https://doi.org/10.1007/978-3-642-12359-7_29 [Google Scholar]
  75. Hardy J. G., Palma M., Wind S. J., and Biggs M. J. Adv. Mater., 2016, 28, (27), 5717 LINK https://doi.org/10.1002/adma.201505417 [Google Scholar]
  76. Linsley C. S., and Wu B. M. Ther. Deliv., 2017, 8, (2), 89 LINK https://doi.org/10.4155/tde-2016-0060 [Google Scholar]
  77. O’Connor A. E., Gallagher W. M., and Byrne A. T. Photochem. Photobiol., 2009, 85, (5), 1053 LINK https://doi.org/10.1111/j.1751-1097.2009.00585.x [Google Scholar]
  78. Kim M. S., and Diamond S. L. Bioorg. Med. Chem. Lett., 2006, 16, (15), 4007 LINK https://doi.org/10.1016/j.bmcl.2006.05.013 [Google Scholar]
  79. Hossion A. M. L., Bio M., Nkepang G., Awuah S. G., and You Y. ACS Med. Chem. Lett., 2013, 4, (1), 124 LINK https://doi.org/10.1021/ml3003617 [Google Scholar]
  80. Ion R.-M., ‘Porphyrins and Phthalocyanines: Photosensitizers and Photocatalysts’, in, “Phthalocyanines and Some Current Applications”, ed. and Yilmaz Y. InTech, London, UK, 2017, pp. 189221 LINK https://doi.org/10.5772/intechopen.68654 [Google Scholar]
  81. Shamay Y., Adar L., Ashkenasy G., and David A. Biomater., 2011, 32, (5), 1377 LINK https://doi.org/10.1016/j.biomaterials.2010.10.029 [Google Scholar]
  82. Cho H. J., Chung M., and Shim M. S. J. Ind. Eng. Chem., 2015, 31, 15 LINK https://doi.org/10.1016/j.jiec.2015.07.016 [Google Scholar]
  83. Huu V. A. N., Luo J., Zhu J., Zhu J., Patel S., Boone A., Mahmoud E., McFearin C., Olejniczak J., de Gracia Lux C., Lux J., Fomina N., Huynh M., Zhang K., and Almutairi A. J. Control. Release, 2015, 200, 71 LINK https://doi.org/10.1016/j.jconrel.2015.01.001 [Google Scholar]
  84. Tomatsu I., Peng K., and Kros A. Adv. Drug Deliv. Rev., 2011, 63, (14–15), 1257 LINK https://doi.org/10.1016/j.addr.2011.06.009 [Google Scholar]
  85. Ruskowitz E. R., and DeForest C. A. Nature Rev. Mater., 2018, 3, (2), 17087 LINK https://doi.org/10.1038/natrevmats.2017.87 [Google Scholar]
  86. Zinger B., and Miller L. L. J. Am. Chem. Soc., 1984, 106, (22), 6861 LINK https://doi.org/10.1021/ja00334a076 [Google Scholar]
  87. Sirivisoot S., Pareta R., and Webster T. J. Nanotechnol., 2011, 22, (8), 85101 LINK https://doi.org/10.1088/0957-4484/22/8/085101 [Google Scholar]
  88. Shen Y., and Wan M. Synth. Met., 1998, 96, (2), 127 LINK https://doi.org/10.1016/s0379-6779(98)00076-9 [Google Scholar]
  89. Pokki J., Ergeneman O., Sivaraman K. M., Özkale B., Zeeshan M. A., Lühmann T., Nelson B. J., and Pané S. Nanoscale, 2012, 4, (10), 3083 LINK https://doi.org/10.1039/c2nr30192j [Google Scholar]
  90. Huang L.-M., Chen C.-H., and Wen T.-C. Electrochim. Acta, 2006, 51, (26), 5858 LINK https://doi.org/10.1016/j.electacta.2006.03.031 [Google Scholar]
  91. Peramo A., Urbanchek M. G., Spanninga S. A., Povlich L. K., Cederna P., and Martin D. C. Tissue Eng. Part A, 2008, 14, (3), 423 LINK https://doi.org/10.1089/tea.2007.0123 [Google Scholar]
  92. Clancy K. F. A., and Hardy J. G. Curr. Pharm. Des., 2017, 23, (24), 3614 LINK https://doi.org/10.2174/1381612823666170710124137 [Google Scholar]
  93. Hardy J. G., Lee J. Y., and Schmidt C. E. Curr. Opin. Biotechnol., 2013, 24, (5), 847 LINK https://doi.org/10.1016/j.copbio.2013.03.011 [Google Scholar]
  94. Hardy J. G., Amend M. N., Geissler S., Lynch V. M., and Schmidt C. E. J. Mater. Chem. B, 2015, 3, (25), 5005 LINK https://doi.org/10.1039/c5tb00106d [Google Scholar]
  95. Hardy J. G., Mouser D. J., Arroyo-Currás N., Geissler S., Chow J. K., Nguy L., Kim J. M., and Schmidt C. E. J. Mater. Chem. B, 2014, 2, (39), 6809 LINK https://doi.org/10.1039/c4tb00355a [Google Scholar]
  96. Li F., Zhu Y., and Wang Y. Microporous Mesoporous Mater., 2014, 200, 46 LINK https://doi.org/10.1016/j.micromeso.2014.07.060 [Google Scholar]
  97. Cheng R., Meng F., Deng C., Klok H.-A., and Zhong Z. Biomater., 2013, 34, (14), 3647 LINK https://doi.org/10.1016/j.biomaterials.2013.01.084 [Google Scholar]
  98. Strozyk M. S., Carregal-Romero S., Henriksen-Lacey M., Brust M., and Liz-Marzán L. M. Chem. Mater., 2017, 29, (5), 2303 LINK https://doi.org/10.1021/acs.chemmater.6b05471 [Google Scholar]
  99. Zhao W., Wei J.-S., Zhang P., Chen J., Kong J.-L., Sun L.-H., Xiong H.-M., and Möhwald H. ACS Appl. Mater. Interfaces, 2017, 9, (22), 18474 LINK https://doi.org/10.1021/acsami.7b02542 [Google Scholar]
  100. Chen X., Zhang Q., Li J., Yang M., Zhao N., and Xu F.-J. ACS Nano, 2018, 12, (6), 5646 LINK https://doi.org/10.1021/acsnano.8b01440 [Google Scholar]
  101. Zhang W., Dai J., Zhang G., Zhang Y., Li S., and Nie D. Nanoscale Res. Lett., 2018, 13, 379 LINK https://doi.org/10.1186/s11671-018-2787-8 [Google Scholar]
  102. Nikjoo D., and Aroguz A. Z. J. Appl. Polym. Sci., 2017, 134, (33), 45143 LINK https://doi.org/10.1002/app.45143 [Google Scholar]
  103. Tønnesen H. H., and Karlsen J. Drug Dev. Ind. Pharm., 2002, 28, (6), 621 LINK https://doi.org/10.1081/ddc-120003853 [Google Scholar]
  104. Morris A. H., Mahal R. S., Udell J., Wu M., and Kyriakides T. R. Adv. Healthcare Mater., 2017, 6, (19), 1700370 LINK https://doi.org/10.1002/adhm.201700370 [Google Scholar]
  105. Lu X., Liu S., Yang X., Han M., and Sun K. J. Pharm. Biomed. Anal., 2019, 164, 181 LINK https://doi.org/10.1016/j.jpba.2018.10.043 [Google Scholar]
  106. Hwang T.-L., Lin Y.-K., Chi C.-H., Huang T.-H., and Fang J.-Y. J. Pharm. Sci., 2009, 98, (10), 3735 LINK https://doi.org/10.1002/jps.21687 [Google Scholar]
  107. Mittal D., Ali A., Md S., Baboota S., Sahni J. K., and Ali J. Drug Deliv., 2014, 21, (2), 75 LINK https://doi.org/10.3109/10717544.2013.838713 [Google Scholar]
  108. Stein S. W., and Thiel C. G. J. Aerosol Med. Pulm. Drug Deliv., 2017, 30, (1), 20 LINK https://doi.org/10.1089/jamp.2016.1297 [Google Scholar]
  109. Pessetto Z. Y., Chen B., Alturkmani H., Hyter S., Flynn C. A., Baltezor M., Ma Y., Rosenthal H. G., Neville K. A., Weir S. J., Butte A. J., and Godwin A. K. Oncotarget, 2017, 8, (3), 4079 LINK https://doi.org/10.18632/oncotarget.13385 [Google Scholar]
  110. Aref A. A. Curr. Opin. Ophthalmol., 2017, 28, (2), 169 LINK https://10.1097/ICU.0000000000000334 [Google Scholar]
  111. Nuxoll E. Adv. Drug Deliv. Rev., 2013, 65, (11–12), 1611 LINK https://doi.org/110.1097/ICU.0000000000000334 [Google Scholar]
  112. Fleming A. B., and Saltzman W. M. Clin. Pharmacokinet., 2002, 41, (6), 403LINK https://doi.org/10.2165/00003088-200241060-00002 [Google Scholar]
  113. Gillies E. R., and Frechet J. M. J. Drug Discov. Today, 2005, 10, (1), 35 LINK https://doi.org/10.1016/s1359-6446(04)03276-3 [Google Scholar]
  114. Huxford R. C., Rocca J. D., and Lin W. Curr. Opin. Chem. Biol., 2010, 14, (2), 262 LINK https://doi.org/10.1016/j.cbpa.2009.12.012 [Google Scholar]
  115. Naldi I., Taranta M., Gherardini L., Pelosi G., Viglione F., Grimaldi S., Pani L., and Cinti C. PLoS One, 2014, 9, (5), e98101 LINK https://doi.org/10.1371/journal.pone.0098101 [Google Scholar]
  116. Stevens H. N. E., Wilson C. G., Welling P. G., Bakhshaee M., Binns J. S., Perkins A. C., Frier M., Blackshaw E. P., Frame M. W., Nichols D. J., Humphrey M. J., and Wicks S. R. Int. J. Pharm., 2002, 236, (1–2), 27 LINK https://doi.org/10.1016/s0378-5173(02)00012-1 [Google Scholar]
  117. Daniels T., Mills N., and Whitaker P. Cochrane Database Syst. Rev., 2013, (4), CD007639 LINK https://doi.org/10.1002/14651858.cd007639.pub2 [Google Scholar]
  118. Wong P. T., and Choi S. K. Chem. Rev., 2015, 115, (9), 3388 LINK https://doi.org/10.1021/cr5004634 [Google Scholar]
  119. Allen T. M., and Cullis P. R. Adv. Drug Deliv. Rev., 2013, 65, (1), 36 LINK https://doi.org/10.1016/j.addr.2012.09.037 [Google Scholar]
  120. De Vries M. H., Van Harten J., Van Bemmel P., and Raghoebar M. Biopharm. Drug Dispos., 1993, 14, (4), 291 LINK https://doi.org/10.1002/bdd.2510140403 [Google Scholar]
  121. Thummel K. E. Adv. Drug Deliv. Rev., 1997, 27, (2–3), 99 LINK https://doi.org/10.1016/s0169-409x(97)00039-2 [Google Scholar]
  122. Lodhi M., Dubey A., Narayan R., Prabhu P., and Priya S. Int. J. Pharm. Investig., 2013, 3, (1), 47 LINK https://doi.org/10.4103/2230-973x.108963 [Google Scholar]
  123. Gomathi T., Govindarajan C., Rose M. H., Sudha P. N., Imran P. K. M., Venkatesan J., and Kim S.-K. Int. J. Pharm., 2014, 468, (1–2), 214 LINK https://doi.org/10.1016/j.ijpharm.2014.04.026 [Google Scholar]
  124. Miao Y., Sun J., Chen G., Lili R., and Ouyang P. Drug Dev. Ind. Pharm., 2016, 42, (8), 1234 LINK https://doi.org/10.3109/03639045.2015.1118496 [Google Scholar]
  125. Lubamba B., Lebacq J., Lebecque P., Vanbever R., Leonard A., Wallemacq P., and Leal T. Am. J. Respir. Crit. Care Med., 2009, 179, (11), 1022 LINK https://doi.org/10.1164/rccm.200901-0049oc [Google Scholar]
  126. Satav S. S., Bhat S., and Thayumanavan S. Biomacromolecules, 2010, 11, (7), 1735 LINK https://doi.org/10.1021/bm1005454 [Google Scholar]
  127. Rostamizadeh K., Vahedpour M., and Bozorgi S. Int. J. Pharm., 2012, 424, (1–2), 67 LINK https://doi.org/10.1016/j.ijpharm.2011.12.054 [Google Scholar]
  128. Tang J., Li J. M., Li G., Zhang H. T., Wang L., Li D., and Ding J. S. Int. J. Nanomedicine, 2017, 12, 6687 LINK https://doi.org/10.2147/ijn.s140569 [Google Scholar]
  129. Balunas M. J., and Kinghorn A. D. Life Sci., 2005, 78, (5), 431 LINK https://doi.org/10.1016/j.lfs.2005.09.012 [Google Scholar]
  130. Ranganath L. R., Milan A. M., Hughes A. T., Dutton J. J., Fitzgerald R., Briggs M. C., Bygott H., Psarelli E. E., Cox T. F., Gallagher J. A., Jarvis J. C., van Kan C., Hall A. K., Laan D., Olsson B., Szamosi J., Rudebeck M., Kullenberg T., Cronlund A., Svensson L., Junestrand C., Ayoob H., Timmis O. G., Sireau N., Le Quan Sang K.-H., Genovese F., Braconi D., Santucci A., Nemethova M., Zatkova A., McCaffrey J., Christensen P., Ross G., Imrich R., and Rovensky J. Ann. Rheum. Dis., 2014, 75, (2), 362 LINK https://doi.org/10.1136/annrheumdis-2014-206033 [Google Scholar]
  131. Patel R. J., Witt D. M., Saseen J. J., Tillman D. J., and Wilkinson D. S. Pharmacotherapy, 2000, 20, (10), 1159 LINK https://doi.org/10.1592/phco.20.15.1159.34585 [Google Scholar]
  132. Trivedi R., Redente E. F., Thakur A., Riches D. W. H., and Kompella U. B. Nanotechnology, 2012, 23, (50), 505101 LINK https://doi.org/10.1088/0957-4484/23/50/505101 [Google Scholar]
  133. Ji T., Lang J., Wang J., Cai R., Zhang Y., Qi F., Zhang L., Zhao X., Wu W., Hao J., Qin Z., Zhao Y., and Nie G. ACS Nano, 2017, 11, (9), 8668 LINK https://doi.org/10.1021/acsnano.7b01026 [Google Scholar]
  134. Detappe A., Nguyen H., Mathieu C., Jiang Y., Agius M., Zavidij O., Berrios B., Shen Y., Johnson J. A., Peter Ghoroghchian P., and Ghobria I. M. Blood, 2018, 132, Suppl. 1, 4681 LINK https://doi.org/10.1182/blood-2018-99-116517 [Google Scholar]
  135. Mastrodicasa M. A., Droege C. A., Mulhall A. M., Ernst N. E., Panos R. J., and Zafar M. A. Expert Opin. Investig. Drugs, 2017, 26, (2), 161 LINK https://doi.org/10.1080/13543784.2017.1276167 [Google Scholar]
  136. Suzuki É. Y., Amaro M. I., de Almeida G. S., Cabral L. M., Healy A. M., and de Sousa V. P. Int. J. Pharm., 2018, 550, (1–2), 89 LINK https://doi.org/10.1016/j.ijpharm.2018.08.035 [Google Scholar]
  137. Park W., Chen J., Cho S., Park S., Larson A. C., Na K., and Kim D.-H. ACS Appl. Mater. Interfaces, 2016, 8, (20), 12711 LINK https://doi.org/10.1021/acsami.6b03505 [Google Scholar]
  138. Kim D. H., Kim M.-D., Choi C.-W., Chung C.-W., Ha S. H., Kim C. H., Shim Y.-H., Jeong Y.-I., and Kang D. H. Nanoscale Res. Lett., 2012, 7, 91 LINK https://doi.org/10.1186/1556-276x-7-91 [Google Scholar]
  139. Grillone A., Riva E. R., Mondini A., Forte C., Calucci L., Innocenti C., de Julian Fernandez C., Cappello V., Gemmi M., Moscato S., Ronca F., Sacco R., Mattoli V., and Ciofani G. Adv. Healthc. Mater., 2015, 4, (11), 1681 LINK https://doi.org/10.1002/adhm.201500235 [Google Scholar]
  140. Denis P. Expert Opin. Pharmacother., 2011, 12, (3), 463 LINK https://doi.org/10.1517/14656566.2011.551007 [Google Scholar]
  141. Tanno F. K., Sakuma S., Masaoka Y., Kataoka M., Kozaki T., Kamaguchi R., Ikeda Y., Kokubo H., and Yamashita S. J. Pharm. Sci., 2008, 97, (12), 5341 LINK https://doi.org/10.1002/jps.21382 [Google Scholar]
  142. Balint R., Cassidy N. J., and Cartmell S. H. Acta Biomater., 2014, 10, (6), 2341 LINK https://doi.org/10.1016/j.actbio.2014.02.015 [Google Scholar]
  143. Brambilla D., Luciani P., and Leroux J.-C. J. Control. Release, 2014, 190, 9 LINK https://doi.org/10.1016/j.jconrel.2014.03.056 [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.1595/205651319X15585277727868
Loading
/content/journals/10.1595/205651319X15585277727868
Loading

Data & Media loading...

  • Article Type: Research Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error