Skip to content
1887
  1. Home
  2. A-Z Publications
  3. Johnson Matthey Technology Review
  4. Volume 69, Issue 1
  5. Article
Volume 69, Issue 1
  • ISSN: 2056-5135
file format pdf download PDF

  • oa Microplasma-Sprayed Titanium and Hydroxyapatite Coatings on Ti6Al4V Alloy: Biocompatibility and Corrosion Resistance: Part I

    Microplasma spraying process coatings with varying porosity and surface roughness

  • Authors: Darya Alontseva1, Yuliya Safarova (Yantsen)2, Sergii Voinarovych3, Aleksei Obrosov4, Ridvan Yamanoglu5, Fuad Khoshnaw6, Assem Nessipbekova7, Aizhan Syzdykova8, Hasan Ismail Yavuz9, Sergii Kaliuzhnyi10, Alexander Krasavin11, Bagdat Azamatov12, Alexandr Khozhanov13, Farkhad Olzhayev14 and Sabine Weiß15
  • Affiliations: 1 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000 Astana, Kazakhstan; School of Digital Technologies and Artificial Intelligence, D. Serikbayev East Kazakhstan Technical University, 19 Serikbayev Street, 070010, Ust-Kamenogorsk, Kazakhstan 2 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000, Astana, Kazakhstan 3 E.O. Paton Electric Welding Institute of NAS of Ukraine, 11 Kazymyr Malevich Street, 03150, Kyiv, Ukraine 4 Department of Physical Metallurgy and Materials Technology, Brandenburg Technical University, Cottbus 03046, Germany 5 Department of Metallurgical and Materials Engineering, Faculty of Engineering, Kocaeli University, 41001, Kocaeli, Türkiye 6 School of Engineering and Sustainable Development, Faculty of Computing, Engineering and Media, De Montfort University, LE1 9BH, Leicester, UK 7 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000, Astana, Kazakhstan 8 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000, Astana, Kazakhstan 9 Department of Metallurgical and Materials Engineering, Faculty of Engineering, Kocaeli University, 41001, Kocaeli, Türkiye 10 E.O. Paton Electric Welding Institute of NAS of Ukraine, 11 Kazymyr Malevich Street, 03150, Kyiv, Ukraine 11 School of Digital Technologies and Artificial Intelligence, D. Serikbayev East Kazakhstan Technical University, 19 Serikbayev Street, 070010, Ust-Kamenogorsk, Kazakhstan 12 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000 Astana, Kazakhstan; Smart Engineering Competence Centre, D. Serikbayev East Kazakhstan Technical University, 19 Serikbayev Street, 070010, Ust-Kamenogorsk, Kazakhstan 13 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000 Astana, Kazakhstan; Smart Engineering Competence Centre, D. Serikbayev East Kazakhstan Technical University, 19 Serikbayev Street, 070010, Ust-Kamenogorsk, Kazakhstan 14 Laboratory of Bioengineering and Regenerative Medicine, National Laboratory Astana, Nazarbayev University, 010000, Astana, Kazakhstan 15 Department of Physical Metallurgy and Materials Technology, Brandenburg Technical University, Cottbus 03046, Germany
    ∞[email protected]; *[email protected]; ¥[email protected]; [email protected]; °[email protected]; §[email protected]; ±[email protected]; ≠[email protected]; ¢[email protected]; ¬[email protected]; **[email protected]; §§[email protected]; ∇[email protected]; ×[email protected]; Φ[email protected]
  • Source: Johnson Matthey Technology Review, Volume 69, Issue 1, Jan 2025, p. 45 - 58
  • DOI: https://doi.org/10.1595/205651325X17201903387613
    • Received: 29 Feb 2024
    • Accepted: 05 Jul 2024

Abstract

This two-part paper investigates the bioactivity and mechanical properties of coatings applied to Ti6Al4V, a common titanium alloy used in endoprosthetic implants. Coatings made from hydroxyapatite (HA) powder and commercially pure titanium (CP-Ti) wires were applied using microplasma spraying. The study focuses on the responses of rat mesenchymal stem cells (MSCs), which are essential for bone healing, to these coatings. Part I shows how adjusting the microplasma spraying process allows coatings with varying porosity and surface roughness to be achieved.

© 2025 Johnson Matthey
This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Loading

Article metrics loading...

/content/journals/10.1595/205651325X17201903387613
2025-01-01
2024-12-21
Loading full text...

Full text loading...

/deliver/fulltext/jmtr/69/1/Safarova_13a_Imp_Pt1.html?itemId=/content/journals/10.1595/205651325X17201903387613&mimeType=html&fmt=ahah

References

  1. V. Kuibida, P. Kokhanets, V. Lopatynska, J. Phys. Educ. Sport, 2021, 21, (3), 1309 LINK https://doi.org/10.7752/jpes.2021.03166
    [Google Scholar]
  2. L. Wang, X. You, L. Zhang, C. Zhang, W. Zou, Bone Res., 2022, 10, (1), 16 LINK https://doi.org/10.1038/s41413-022-00190-4
    [Google Scholar]
  3. S. Arabnejad, B. Johnston, M. Tanzer, D. Pasini, J. Orthop. Res., 2017, 35, (8), 1774 LINK https://doi.org/10.1002/jor.23445
    [Google Scholar]
  4. M. Fousova, D. Vojtech, E. Jablonska, J. Fojt, J. Lipov, Materials, 2017, 10, (9), 987 LINK https://doi.org/10.3390/ma10090987
    [Google Scholar]
  5. M. Saini, Y. Singh, P. Arora, V. Arora, K. Jain, World J. Clin. Cases, 2015, 3, (1), 52 LINK https://doi.org/10.12998/wjcc.v3.i1.52
    [Google Scholar]
  6. J. Wilson, ‘Metallic Biomaterials: State of the Art and New Challenges’, in “Fundamental Biomaterials: Metals”, eds. P. Balakrishnan, M. S. Sreekala, S. Thomas, Woodhead Publishing, Cambridge, UK, 2018, pp. 1–33 LINK https://doi.org/10.1016/B978-0-08-102205-4.00001-5
    [Google Scholar]
  7. V. Vishwakarma, G. S. Kaliaraj, K. K. A. Mosas, Coatings, 2023, 13, (1), 69 LINK https://doi.org/10.3390/coatings13010069
    [Google Scholar]
  8. D. Alontseva, B. Azamatov, Y. Safarova (Yantsen), S. Voinarovych, G. Nazenova, Coatings, 2023, 13, (7), 1175 LINK https://doi.org/10.3390/coatings13071175
    [Google Scholar]
  9. J. Sánchez-Bodón, J. A. Del Olmo, J. M. Alonso, I. Moreno-Benítez, J. L. Vilas-Vilela, L. Pérez-Álvarez, Polymers, 2022, 14, (1), 165 LINK https://doi.org/10.3390/polym14010165
    [Google Scholar]
  10. T. Stich, F. Alagboso, T. Křenek, T. Kovářík, V. Alt, D. Docheva, Bioeng. Transl. Med., 2022, 7, (1), e10239 LINK https://doi.org/10.1002/btm2.10239
    [Google Scholar]
  11. B. Jahani, X. Wang, Biomed. J. Sci. Tech. Res., 2021, 38, (1), 30058 LINK https://doi.org/10.26717/bjstr.2021.38.006104
    [Google Scholar]
  12. E. A. Lewallen, W. H. Trousdale, R. Thaler, J. J. Yao, W. Xu, J. M. Denbeigh, A. Nair, J.-P. Kocher, A. Dudakovic, D. J. Berry, R. C. Cohen, M. P. Abdel, D. G. Lewallen, A. J. van Wijnen, Tissue Eng. Part A, 2021, 27, (23–24), 1503 LINK https://doi.org/10.1089/ten.TEA.2020.0369
    [Google Scholar]
  13. R. F. Heary, N. Parvathreddy, S. Sampath, N. Agarwal, J. Spine Surg., 2017, 3, (2), 163 LINK https://doi.org/10.21037/jss.2017.05.01
    [Google Scholar]
  14. ‘Implants for Surgery. Hydroxyapatite—Thermally Sprayed Coatings of Hydroxyapatite’, BS ISO 13779-2:2018, The British Standards Institution, London, UK, 31st December, 2018 LINK https://knowledge.bsigroup.com/products/implants-for-surgery-hydroxyapatite-thermally-sprayed-coatings-of-hydroxyapatite?version=tracked
    [Google Scholar]
  15. D. L. Alontseva, E. Ghassemieh, S. Voinarovych, A. Russakova, O. Kyslytsia, Y. Polovetskyi, A. Toxanbayeva, J. Microsc., 2020, 279, (3), 148 LINK https://doi.org/10.1111/jmi.12849
    [Google Scholar]
  16. D. Alontseva, E. Ghassemieh, S. Voinarovych, O. Kyslytsia, Y. Polovetskyi, N. Prokhorenkova, A. Kadyroldina, Johnson Matthey Technol. Rev., 2020, 64, (2), 180 LINK https://doi.org/10.1595/205651320x15737283268284
    [Google Scholar]
  17. A. Kadyroldina, D. Alontseva, S. Voinarovych, L. Łatka, O. Kyslytsia, B. Azamatov, A. Khozhanov, N. Prokhorenkova, A. Zhilkashinova, S. Burburska, Mater. Sci., 2022, 40, (4), 28 LINK https://doi.org/10.2478/msp-2022-0043
    [Google Scholar]
  18. D. L. Alontseva, M. B. Abilev, A. M. Zhilkashinova, S. G. Voinarovych, O. N. Kyslytsia, E. Ghassemieh, A. Russakova, L. Łatka, Adv. Mater. Sci., 2018, 18, (3), 79 LINK https://doi.org/10.1515/adms-2017-0043
    [Google Scholar]
  19. K. Yushenko, Yu. Borisov, S. Voynarovych, O. Fomakin, ‘Plasmatron for Spraying of Coatings’, World Patent Appl. 2004/010747
     [Google Scholar]
  20. T. Stich, F. Alagboso, T. Křenek, T. Kovářík, V. Alt, D. Docheva, Bioeng. Transl. Med., 2022, 7, (1), e10239 LINK https://doi.org/10.1002/btm2.10239
    [Google Scholar]
  21. A. Civantos, A. M. Beltrán, C. Domínguez-Trujillo, M. D. Garvi, J. Lebrato, J. A. Rodríguez-Ortiz, F. García-Moreno, J. V. Cauich-Rodriguez, J. J. Guzman, Y. Torres, Metals, 2019, 9, (10), 1039 LINK https://doi.org/10.3390/met9101039
    [Google Scholar]
  22. A. Pandey, A. Awasthi, K. K. Saxena, Adv. Mater. Process. Technol., 2020, 6, (2), 405 LINK https://doi.org/10.1080/2374068x.2020.1731236
    [Google Scholar]
  23. L. E. Murr, J. Mater. Sci. Technol., 2019, 35, (2), 231 LINK https://doi.org/10.1016/j.jmst.2018.09.003
    [Google Scholar]
  24. M. J. Shivaram, S. B. Arya, J. Nayak, B. B. Panigrahi, Mater. Today Proc., 2020, 33, (8), 5257 LINK https://doi.org/10.1016/j.matpr.2020.02.952
    [Google Scholar]
  25. S. Yavuz, M. T. Özkan, Politek. Derg., 2022, 25, (2), 827 LINK https://doi.org/10.2339/politeknik.1074516
    [Google Scholar]
  26. S. Ali, A. M. A. Rani, Z. Baig, S. W. Ahmed, G. Hussain, K. Subramaniam, S. Hastuty, T. V. V. L. N. Rao, Corros. Rev., 2020, 38, (5), 381 LINK https://doi.org/10.1515/corrrev-2020-0001
    [Google Scholar]
  27. N. Eliaz, Materials, 2019, 12, (3), 407 LINK https://doi.org/10.3390/ma12030407
    [Google Scholar]
  28. K. Sun, R. Fu, X. W. Liu, L. M. Xu, G. Wang, S. Y. Chen, Q. J. Zhai, S. Pauly, Bioact. Mater., 2022, 8, 253 LINK https://doi.org/10.1016/j.bioactmat.2021.06.018
    [Google Scholar]
  29. Y. Zhang, N. Sun, M. Zhu, Q. Qiu, P. Zhao, C. Zheng, Q. Bai, Q. Zeng, T. Lu, Biomater. Adv., 2022, 133, 112651 LINK https://doi.org/10.1016/j.msec.2022.112651
    [Google Scholar]
  30. C. Wang, D. Xu, L. Lin, S. Li, W. Hou, Y. He, L. Sheng, C. Yi, X. Zhang, H. Li, Y. Li, W. Zhao, D. Yu, Mater. Sci. Eng. C, 2021, 131, 112499 LINK https://doi.org/10.1016/j.msec.2021.112499
    [Google Scholar]
  31. R. Wang, S. Ni, L. Ma, M. Li, Front. Bioeng. Biotechnol., 2022, 10, 973297 LINK https://doi.org/10.3389/fbioe.2022.973297
    [Google Scholar]
  32. V. I. Kalita, D. A. Malanin, A. I. Mamaev, V. A. Mamaeva, V. V. Novochadov, D. I. Komlev, V. S. Komlev, A. A. Radyuk, Materialia, 2021, 15, 101018 LINK https://doi.org/10.1016/j.mtla.2021.101018
    [Google Scholar]
  33. A. Canabarro, G. E. Crippa, M. U. Shirozaki, E. M. Sampaio, L.-P. Lefebvre, P. T. De Oliveira, M. M. Beloti, A. L. Rosa, J. Osseointegr., 2011, 3, (1), 17 LINK https://doi.org/10.23805/jo.2011.03.01.03
    [Google Scholar]
  34. F. Matassi, A. Botti, L. Sirleo, C. Carulli, M. Innocenti, Clin. Cases Miner. Bone Metab., 2013, 10, (2), 111 LINK https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796997/
    [Google Scholar]
  35. ‘Implants for Surgery — Metallic Materials — Part 3: Wrought Titanium 6-Aluminium 4-Vanadium Alloy’, ISO 5832-3:2021, International Organization for Standardization, Geneva, Switzerland, November, 2021, 8 pp LINK https://www.iso.org/standard/79626.html
    [Google Scholar]
  36. ‘Wrought Titanium and Titanium Alloys. Grades’, GOST 19807-91, Euro-Asian Council for Standardization Metrology Certification (EASC), Russia, 1991 LINK https://gostperevod.com/gost-19807-91.html
    [Google Scholar]
  37. ‘Standard Specification for Composition of Medical-Grade Hydroxylapatite for Surgical Implants’, ASTM F1185-23, ASTM International, West Conshohocken, USA, 2023 LINK https://doi.org/10.1520/F1185-03R14
    [Google Scholar]
  38. ‘Standard Test Methods for Determining Area Percentage Porosity in Thermal Sprayed Coatings’, ASTM E2109-01(2021), ASTM International, West Conshohocken, USA, 2021 LINK https://doi.org/10.1520/E2109-01R21
    [Google Scholar]
  39. A. Moltasov, M. Dyman, S. Kaliuzhnyi, I. Mossokovska, S. Voinarovych, O. Kyslytsia, E. Koytchev, Ser. Biomech., 2022, 36, (2), 141 LINK https://doi.org/10.7546/sb.36.2022.02.14
    [Google Scholar]
  40. ‘Standard Test Method For Tension Testing of Calcium Phosphate and Metallic Coatings’, ASTM F1147-24, ASTM International, West Conshohocken, USA, 2024 LINK https://doi.org/10.1520/F1147-24
    [Google Scholar]
  41. ‘Geometrical Product Specifications (GPS) — Surface Texture: Areal-Metrological Characteristics for Areal Topography Measuring Methods’, BS EN ISO 25178-600:2019, The British Standards Institution, London, UK, 30th April, 2019 LINK https://doi.org/10.3403/30333745u
    [Google Scholar]
  42. C. A. Schneider, W. S. Rasband, K. W. Eliceiri, Nat. Methods, 2012, 9, (7), 671 LINK https://doi.org/10.1038/nmeth.2089
    [Google Scholar]
  43. M. Pereira, J. Pinto, B. Arteaga, A. Guerra, R. N. Jorge, F. J. Monteiro, C. L. Salgado, Int. J. Mol. Sci., 2023, 24, (24), 17625 LINK https://doi.org/10.3390/ijms242417625
    [Google Scholar]
  44. N. M. Geekiyanage, M. A. Balanant, E. Sauret, S. Saha, R. Flower, C. T. Lim, Y. Gu, PLoS One, 2019, 14, (4), e0215447 LINK https://doi.org/10.1371/journal.pone.0215447
    [Google Scholar]
  45. Darya Alontseva, Yuliya Safarova (Yantsen), Sergii Voinarovych, Aleksei Obrosov, Ridvan Yamanoglu, Fuad Khoshnaw, Assem Nessipbekova, Aizhan Syzdykova, Hasan Ismail Yavuz, Sergii Kaliuzhnyi, Alexander Krasavin, Bagdat Azamatov, Alexandr Khozhanov, Farkhad Olzhayev, Sabine Weiß, Johnson Matthey Technol. Rev., 2025, 69, (1), 59 LINK https://doi.org/10.1595/205651325X17290035905758
    [Google Scholar]
/content/journals/10.1595/205651325X17201903387613
Loading
Microplasma-Sprayed Titanium and Hydroxyapatite Coatings on Ti6Al4V Alloy: in vitro Biocompatibility and Corrosion Resistance: Part I
Johnson Matthey Technology Review 69, 45 (2025); https://doi.org/10.1595/205651325X17201903387613
/content/journals/10.1595/205651325X17201903387613
/content/journals/10.1595/205651325X17201903387613
Loading

Data & Media loading...

  • Article Type: Review Article
Keyword(s): biocompatible coatings; elastic modulus; endoprosthesis implants; in vitro test; porosity; surface roughness

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test